Latest Aussie DFD research released in April

It’s been a busy month for DFD research so far in April – so check out the latest in research below!

Availability and service provision of multidisciplinary diabetes foot units in Australia: a cross-sectional survey

Vo UG, Gilfillan M, Hamilton EJ, Manning L, Munshi B, Hiew J, Norman PE, Ritter JC.

With growing global prevalence of diabetes mellitus, diabetes-related foot disease (DFD) is contributing significantly to disease burden. As more healthcare resources are being dedicated to the management of DFD, service design and delivery is being scrutinised. Through a national survey, this study aimed to investigate the current characteristics of services which treat patients with DFD in Australia.


Twenty-four-month outcomes of drug-coated balloon in diabetic patients in the BIOLUX P-III registry: a subgroup analysis.

Mwipatayi BP, Barry IP, Brodmann M, Zeller T, Varcoe RL, Moscovic M, Chian JWC, Christensen JK, Yahaya SA, Oshin OA, Tepe G; BIOLUX P-III Global Registry Investigators.
This study aims to assess the use of drug-coated balloon (DCB) in a large patient population under real-world conditions and, specifically, analyse the impact of diabetes mellitus on long term outcomes following DCB utilisation.


Effects of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes in women versus men.

RĂ„dholm K, Zhou Z, Clemens K, Neal B, Woodward M.
Sodium-glucose co-transporter-2 (SGLT2) inhibitors prevent cardiovascular complications in type 2 diabetes. We aimed to study whether they have similar effects in women and men by summarizing the effects of SGLT2 inhibitors compared to placebo on vascular and safety outcomes stratified by sex.


Novel Transfer Learning Approach for Medical Imaging with Limited Labeled Data.
Alzubaidi L, Al-Amidie M, Al-Asadi A, Humaidi AJ, Al-Shamma O, Fadhel MA, Zhang J, SantamarĂ­a J, Duan Y.


C-reactive protein predicts complications in community-associated S. aureus bacteraemia: a cohort study.
Botheras CL, Bowe SJ, Cowan R, Athan E.
Staphylococcus aureus (S. aureus) bacteraemia is increasingly acquired from community settings and is associated with a mortality rate of up to 40% following complications. Identifying risk factors for complicated S. aureus bacteraemia would aid clinicians in targeting patients that benefit from expedited investigations and escalated care.

Lower extremity amputations in Ireland: a registry-based study.
Mealy A, Tierney S, Sorensen J.
To analyse the current provision of lower extremity amputations (LEA) in Irish public hospitals by patient characteristics and assess the potential savings for reducing numbers if a national multi-disciplinary foot protection clinic (MDFPC) was established nation-wide.

A multiomics approach to identify host-microbe alterations associated with infection severity in diabetic foot infections: a pilot study.
Radzieta M, Sadeghpour-Heravi F, Peters TJ, Hu H, Vickery K, Jeffries T, Dickson HG, Schwarzer S, Jensen SO, Malone M.
Diabetic foot infections (DFIs) are a major cause of hospitalization and can lead to lower extremity amputation. In this pilot study, we used a multiomics approach to explore the host-microbe complex within DFIs.

Evidence-Based Recommendations for Medical Management of Peripheral Artery Disease.
Golledge J, Drovandi A.
The aim of this narrative review was to summarize the current evidence on the medical management of PAD in order to inform clinicians and highlight recommendations for clinical practice.


Have you had your say about the new Australian Guidelines for diabetes-related foot disease? Public consultation is open until the 27th April – learn more at