Latest Aussie Research for April

Check out the latest Aussie research released in the last few weeks!

Factors associated with adherence to using removable cast walker treatment among patients with diabetes-related foot ulcers.
Ababneh A, Finlayson K, Edwards H, Lazzarini PA.
Adherence to using knee-high offloading treatment is critical for healing diabetes-related foot ulcers (DFUs). However, few studies have investigated patients’ adherence to using knee-high offloading treatment. We aimed to investigate the levels and factors associated with adherence to using knee-high removable cast walker (RCW) treatment among patients with DFUs
BMJ Open Diabetes Res Care. 2022 Feb;10(1):e002640. doi: 10.1136/bmjdrc-2021-002640.
PMID: 35144940

Prevalence and risk factors of lower limb amputations in patients with diabetic foot ulcers: A systematic review and meta-analysis.
Rodrigues BT, Vangaveti VN, Urkude R, Biros E, Malabu UH.
The study aimed at determining prevalence and risk factors (RFs) of diabetic lower limb amputations (LLAs).
Diabetes Metab Syndr. 2022 Feb;16(2):102397. doi: 10.1016/j.dsx.2022.102397. Epub 2022 Jan 14.
PMID: 35085918 Review.

Topical oxygen therapy for diabetes-related foot ulcers: A systematic review and meta-analysis.
Thanigaimani S, Singh T, Golledge J.
Topical oxygen therapy (TOT) has been suggested as a treatment for diabetes-related foot ulcer (DFU) but no prior meta-analyses of randomised clinical trials (RCT) have been reported. This systematic review and meta-analysis examined the randomised evidence for the benefit of TOT in healing DFU.
Diabet Med. 2021 Aug;38(8):e14585. doi: 10.1111/dme.14585. Epub 2021 Apr 29.
PMID: 33871095

Effect of enriched oxygen inhalation on lower limb skin temperatures in diabetic and healthy humans: a pilot study.
Au-Yeung KL, Selvaraj C, Amin T, Ma LK, Bennett MH.
Measurement of skin temperature with infrared thermometry has been utilised for assessing metabolic activity and may be useful in identifying patients with ulcers suitable for hyperbaric oxygen treatment and monitoring their treatment progress. Since oxygen promotes vasoconstriction in the peripheral circulation, we hypothesised that oxygen administration may lower skin temperature and complicate the interpretation of temperatures obtained. This pilot study investigated the effect of oxygen administration on lower limb skin temperature in healthy subjects and diabetic patients.
Diving Hyperb Med. 2022 Mar 31;52(1):2-6. doi: 10.28920/dhm52.1.2-6.
PMID: 35313366

Ischemic heart disease and its risk factors in patients with diabetic foot ulcers: A systematic review and meta-analysis.
Waheed FNM, Vangaveti VN, Malabu UH.
There is limited literature on IHD in DFU patients. This review aimed to determine the prevalence of and risk factors of IHD in patients with DFUs.
Diabetes Metab Syndr. 2022 Feb;16(2):102414. doi: 10.1016/j.dsx.2022.102414. Epub 2022 Jan 25.
PMID: 35104751 Review.

Severe mental illness and the risk of diabetes complications. A nationwide register-based cohort study.
Scheuer SH, Kosjerina V, Lindekilde N, Pouwer F, Carstensen B, Jørgensen ME, Benros ME, Andersen GS.
J Clin Endocrinol Metab. 2022 Mar 31:dgac204. doi: 10.1210/clinem/dgac204. Online ahead of print.
PMID: 35359003