New Aussie Research in August

Check out the latest in DFD Aussie research released in the last few weeks.

Routine bacterial culture of proximal bone specimens during minor amputation in patients with diabetes-related foot infections has little clinical utility in predicting re-operation or ulcer healing.
Voon K, Vo UG, Hand R, Hiew J, Ritter JC, Hamilton EJ, Manning L.
The study examined the concordance of microbiological results from proximal bone cultures compared to results from superficial wound swabs in relation to patient outcomes; with the aim of determining the utility of routinely obtaining marginal bone specimens.
J Foot Ankle Res. 2022 Aug 20;15(1):64. doi: 10.1186/s13047-022-00563-2.
PMID: 35987828

Metatranscriptome sequencing identifies Escherichia are major contributors to pathogenic functions and biofilm formation in diabetes related foot osteomyelitis.
Radzieta M, Malone M, Ahmad M, Dickson HG, Schwarzer S, Jensen SO, Lavery LA.
In this study RNA-sequencing was employed to explore microbial metatranscriptomes with a view to understand the relative activity and functions of the pathogen/s responsible for diabetes foot osteomyelitis (DFO).
Front Microbiol. 2022 Aug 1;13:956332. doi: 10.3389/fmicb.2022.956332. eCollection 2022.
PMID: 35979499 Free PMC article.

The utility of hyperspectral imaging in patients with chronic venous disorders.
Hart O, Adeane S, Vasudevan T, van der Werf B, Khashram M.
The aim of this study was to determine if transcutaneous oxygenation in the lower limb, as measured by HSI, changes depending on the clinical component of CEAP classification in CVD.
J Vasc Surg Venous Lymphat Disord. 2022 Aug 9:S2213-333X(22)00341-9. doi: 10.1016/j.jvsv.2022.07.001. Online ahead of print.
PMID: 35961628

Near Infrared Spectroscopy in peripheral artery disease and the diabetic foot: A systematic review.
Joseph S, Munshi B, Agarini R, Ho Kwok RC, Green DJ, Jansen S.
Diabetes Metab Res Rev. 2022 Aug 8:e3571. doi: 10.1002/dmrr.3571. Online ahead of print.
PMID: 35939767 Review.

Effect of Sensory Neuropathy on the Predictive Value of Inflammatory Biomarkers for Osteomyelitis in Diabetic and Nondiabetic Patients with Foot Infections.
Ryan E, Ahn J, Wukich DK, Fontaine J, Crisologo PA, Malone M, Oz OK, Lavery LA.
TThe study investigates the predictive value of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in persons with and without diabetes with osteomyelitis (OM).
J Am Podiatr Med Assoc. 2022 Apr 27;112(2):20-168. doi: 10.7547/20-168.
PMID: 33142316

Fear of Falling and Functional Mobility in Elders with Diabetic Peripheral Neuropathy in Coastal Karnataka, India: A Hospital-Based Study.
Gupta G, Maiya GA, Bhat SN, Hande MH, Dillon L, Keay L.
The study investigates fear of falling and functional mobility, as an approximate measure of clinical fall risk, and explore the associated risk factors in elderly diabetic neuropathy patients living in coastal Karnataka, India.
Curr Aging Sci. 2022 Aug 4;15(3):252-258. doi: 10.2174/1874609815666220324153104.
PMID: 35331103