Check out the latest Aussie DFD research released in the last few weeks.
Wound healing with “spray-on” autologous skin grafting (ReCell) compared with standard care in patients with large diabetes-related foot wounds: an open-label randomised controlled trial.
The aim of this trial was to assess the potential benefit of spray‐on skin as a superior and cost‐effective management strategy for diabetes‐related foot wounds.
Manning L, Ferreira IB, Gittings P, Hiew J, Ryan E, Baba M, Raby E, Carville K, Norman PE, Davis WA, Wood F, Hamilton EJ, Ritter JC.
Int Wound J. 2022 Mar;19(3):470-481. doi: 10.1111/iwj.13646. Epub 2021 Jun 22.
PMID: 34156758 Free PMC article. Clinical Trial.
The burden of diabetes-related foot disease among older adults in Australia.
Diabetes-related foot disease (DFD) is imposing an enormous burden on the health system and society due to the rapid growth of diabetes worldwide. Given the paucity of robust data on the disease burden of DFD in Australia, this study aimed to estimate the burden of disease due to DFD.
Ahmed MU, Tannous WK, Agho KE, Henshaw F, Turner D, Simmons D.
Int Wound J. 2022 Mar 5. doi: 10.1111/iwj.13781. Online ahead of print.
Opinions about the most appropriate surgical management of diabetes-related foot infection: a cross-sectional survey.
There is a lack of high quality evidence to guide the optimal management of diabetes-related foot infection, particularly in cases of severe diabetes-related foot infection and diabetes-related foot osteomyelitis. This study examined the opinions of surgeons about the preferred management of severe diabetes-related foot infection.
Seng L, Drovandi A, Fernando ME, Golledge J.
J Foot Ankle Res. 2022 Mar 2;15(1):18. doi: 10.1186/s13047-022-00523-w.
Cutaneous microvascular reactivity in Charcot neuroarthropathy: a systematic review and meta-analysis.
To systematically evaluate the literature investigating the relationship between cutaneous microvascular reactivity in the foot of adults with diabetes-related Charcot neuroarthropathy compared to a non-Charcot adult control group.
Lanting SM, Chan TL, Casey SL, Peterson BJ, Chuter VH.
J Foot Ankle Res. 2022 Mar 1;15(1):17. doi: 10.1186/s13047-022-00522-x.
PMID: 35232466 Review.
Novel therapeutic targets for diabetes-related wounds or ulcers: an update on preclinical and clinical research.
This review summarizes recent preclinical and clinical research on novel diabetes-related wound treatments. Animal models of diabetes-related wounds and recent studies testing novel therapeutic agents in these models are described. Findings from clinical trials are also discussed. Finally, challenges to identifying and implementing novel therapies are described.
Golledge J, Thanigaimani S.
Expert Opin Ther Targets. 2021 Dec;25(12):1061-1075. doi: 10.1080/14728222.2021.2014816. Epub 2021 Dec 22.
PMID: 34873970 Review.
The clustering of Cardiovascular, Renal, Adipo-Metabolic Eye and Liver disease with type 2 diabetes.
This review will explore the sticky, brittle conglomeration of CArdiac, Renal, Adipo-Metabolic, Eye and Liver disease (hereafter collectively known as CARAMEL disease) that is coincident in most patients with type 2 diabetes and contextualise the recent changes in diabetes guidelines that now specifically focus on identifying and aggressively managing these high-risk individuals with it.
Metabolism. 2022 Mar;128:154961. doi: 10.1016/j.metabol.2021.154961. Epub 2021 Dec 24.
PMID: 34958818 Review.
Determining the role of SGLT2 inhibition with Empagliflozin in the development of diabetic retinopathy.
Matthews J, Herat L, Rooney J, Rakoczy E, Schlaich M, Matthews VB.
Biosci Rep. 2022 Mar 31;42(3):BSR20212209. doi: 10.1042/BSR20212209.
Development and Usability Evaluation of a Telemedicine System for Management and Monitoring of Patients with Diabetic Foot.
The aim of the present study was to develop and evaluate the usability of a telemedicine system for management and monitoring of patients with diabetic foot.
Bahaadinbeigy K, Sheikhtaheri A, Fatehi F, Moulaei K.
Healthc Inform Res. 2022 Jan;28(1):77-88. doi: 10.4258/hir.2022.28.1.77. Epub 2022 Jan 31.